Emend ,80 mg ,1 capsule

Do not take

If you are allergic to aprepitant or any of the other components of this medicine (listed in section 6).

together with medicines containing pimozide (medicines used to treat certain mental disorders), terfenadine and astemizole (medicines used to treat hay fever and other allergies) or cisapride (medicines used to treat indigestion). Tell your doctor if you are taking these medicines because your treatment needs to be changed before you start taking EMEND.

Warnings and Precautions

Please talk with your doctor, pharmacist, or nurse before taking EMEND.

Tell your doctor if you have liver disease before treatment with EMEND, because your liver is important for the breakdown of this medicine in your body. Your doctor may need to monitor your liver.

Children and teens

EMEND is not intended for use in children and adolescents under the age of 18 years.

Taking other medicines

EMEND may affect other medicines during and after treatment. Some medicines should not be taken with EMEND (for example, pimozide, terfenadine, astemizole, and cisapride); Some other medicines require a dose adjustment for the drug (see also under the section “EMEND should not be taken”).

The effects of EMEND or other medicines can be affected if you use EMEND together with, for example, B. Use the following medicines listed below.

Contraceptives, including pills, skin patches, implants, and some hormonal coils, may not work properly when used with EMEND. Use a different or additional method of contraception during EMEND treatment and within 2 months after EMEND treatment.

Cyclosporin, tacrolimus, sirolimus, everolimus (immunosuppressants),

Alfentanil, fentanyl (medicines used to treat pain),

Quinidine (used to treat irregular heartbeats)

Irinotecan, etoposide, vinorelbine (drugs used to treat cancer),

Medicines containing ergot alkaloid derivatives such as ergotamine and dihydroergotamine (used to treat migraines)

Warfarin, acenocumarol (a blood thinner; blood tests may be required),

Rifampicin, clarithromycin, telithromycin (antibiotics used to treat infections),

Phenytoin (used to treat seizures)

Carbamazepine (used to treat depression and epilepsy),

Midazolam, triazolam, phenobarbital (medicines for sedation or sleep),

St. John's wort (a herbal medicine for treating depression),

Protease inhibitors (medications used to treat HIV infections),

Ketoconazole (except shampoo), itraconazole, voriconazole, posaconazole (medications for treating fungal infections),

Nefazodone (a cure for depression),

Cortisone preparations (such as dexamethasone and methylprednisolone),

Medications for anxiety (such as alprazolam) and

Tolbutamide (a medicine used to treat diabetes).

Tell your doctor or pharmacist if you are taking, have recently taken or plan to take other medicines.

During pregnancy and breastfeeding

You should not take EMEND during pregnancy unless it is clearly necessary. If you are pregnant or breastfeeding, think you are pregnant, or plan to have a baby, consult your doctor for advice before taking this medicine.

For contraception, see the section “Taking other medicines with EMEND.”

It is not known whether EMEND is excreted in human milk; Therefore, breastfeeding is not recommended during treatment with EMEND.

Be sure to contact your doctor before taking EMEND if you are breast-feeding or are planning to breast-feed.

Driving and using cars

Keep in mind that some people may feel dizzy or drowsy after taking EMEND. If you feel dizzy or drowsy, you should avoid driving or using cars after taking EMEND (see "What side effects are possible?").

EMEND contains sucrose

EMEND contains sucrose. If your doctor has told you that you cannot tolerate certain types of sugar, consult your doctor before taking this medicine.

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